Current Studies
Our latest study is underway featuring 40+ new Pilot Pups!
Pilot Pups are stray dogs who we have rescued from the streets. We've nicknamed them Pilot Pups because we include them in our pilot studies to develop the One-Dose Spay and Neuter Cookie.
Each Pilot Pup eats a single trial Cookie. The trial Cookie is formulated to have a safe, low dose of the birth control ingredients we’re studying.
A month later, each Pup has a normal spay/neuter surgery so that pathologists can examine the treated ovaries/testes that are removed during the surgery.
By studying these treated ovaries/testes, we can determine the effectiveness of each trial Cookie. The more follicles that are impaired (the higher the "count") the better, and the closer the Pilot Pup is to being infertile.
Last but not least, our Pups live in loving homes, not laboratories.
Each Pilot Pup is adopted into a forever home.
Trial start date 6.7.22, Surgery date 7.7.22
A microscopic image of Axil’s ovaries, removed during routine spay and neuter surgery.
Axil
It was a dangerously hot day when Axil was rescued – well over 100 degrees Fahrenheit. A 600 team member found her panting and looking for shade. The team member immediately offered her water and brought her to the vet. She is a friendly and active dog who loves the company of others!
Trial start date 6.7.22, Surgery date 7.7.22
A microscopic image of Ali's ovaries. One of the compounds we are examining to produce infertility is VCD: Vinylcyclohexene dioxide, CAS. No. 106-87-6, C8H12O2. As a multiple-dose formula, it has been studied for years, and it is already approved for use in the U.S. by the EPA to produce infertility in rodents.
Ali
Ali was found on the streets, very skinny and afraid of humans.
At first her rescuers thought she was suffering from some disease.
She was brought to the vet clinic for a bath and an exam, and it turned out she was fine. Now she is healthy and safe.
Trial start date 6.7.22, Surgery date 7.7.22
Bruni’s ovaries were removed during routine spay surgery. Her ovarian follicles will be analyzed to determine how many were rendered non-viable by certain compounds in the Cookie that cause infertility. Once enough viable follicles become non-viable, permanent infertility is the result. In adult human females, this is a safe and natural condition that occurs at menopause.
Bruni
Bruni was found wandering around a construction site.
Her rescuer described Bruni immediately running towards her, as if she were grateful to have been found!
She was brought to the vet for a checkup. She is a happy and playful dog!
Trial start date 6.27.22, Surgery date 7.27.22
Stacy’s ovaries under a microscope. For the safety of the Pilot Pup, we only increase key ingredients by very small, controlled amounts, one tiny step at a time.
Stacy
A 600 team member received a call from a nearby residence about a dog barking constantly. Stacy was found hiding in the bushes, suffering from a leg injury,and her hind legs were very weak. She was also emaciated. Her rescuer gaver her food and water and brought her to the vet for treatment. She is now a happy dog.
Trial start date 6.27.22, Surgery date 7.27.22
Ovaries of Pilot Pup Bo. The more follicles that are impaired, the better, since that means the dog is closer to being infertile.
Bo
A 600 team member received a call from a motorcyclist who nearly hit a dog in the road. The team member arrived on the scene to rescue Bo, who at first was terrified and very hungry. Her rescuer slowly earned her trust. She was treated for a skin infection that had caused her to lose some of her fur. Now she is a very playful dog who loves going on walks!
Trial start date 9.22.22, Surgery date 10.25.22
Avery's histology photo coming soon!
Avery
Avery is a very alert dog. One of the 600 team members went to assess Avery when they were told where to find her. The team member was told that people were keeping the local dogs regularly dewormed, but Avery was a newcomer and they were concerned that she would infect the others. The team member rescued her and took her straight to our vet. Avery was evaluated and diagnosed with a skin condition which has since been treated.
Trial start date 6.27.22, Surgery date 7.28.22
Chase’s ovarian follicles under a microscope. In our current study, 30 days after each rescued Pilot Pup is given a trial One-Dose Spay and Neuter Cookie, the dog undergoes routine spay or neuter surgery. The reproductive tissues that are removed as part of the surgery – ovaries in females, testes in males – are preserved rather than discarded. This allows scientists to analyze the effectiveness of the Cookie.
Chase
A 600 team member received a call about children throwing rocks at a dog who was terrified and trying to hide. The team member arrived on the scene to find Chase.At first she was too scared to trust anyone, but her rescuer gave her treats and affection and slowly earned her trust. She had some minor bruises. She was brought to the vet and given first aid, and now enjoys spending time with other dogs.
Trial start date 6.27.22, Surgery date 7.28.22
Oreo’s ovaries were removed during routine spay surgery. Her ovarian follicles will be reviewed by multiple veterinary pathologists to determine the effectiveness of the Cookie she received.
Oreo
Oreo was found soaking wet and looking for shelter during a rainstorm. Her rescuer, a 600 team member, brought her indoors to dry her off and offer her water and treats. Oreo immediately began licking her rescuer … as if she knew she was being rescued. She loves to play with humans and with other dogs!
Trial start date 6.27.22, Surgery date 7.28.22
A microscopic image of Rose’s ovaries, removed during routine spay surgery. We are investigating multiple different compounds known to impair ovarian follicles, in order to determine what is most effective for producing infertility.
Rose
Rose was found suffering from a skin condition. She was also reluctant to move her hind legs, and when she did, she dragged them. But she was courageous and happy to get help. A 600 team member rescued her and brought her to the vet for treatment, and her condition improved.
Trial start date 6.27.22, Surgery date 7.29.22
Pilot Pup Lola’s ovaries, removed during routine spay surgery. Under higher magnification, her ovarian follicles will be examined to determine the effectiveness of the Cookie she received.
Lola
Lola was rescued by a 600 team member who found her while out on a walk. Her rescuer heard barking and followed the sound over to a house that was under construction. She found Lola lying in a pile of sand, looking hungry and scared. Lola was rescued and brought to the vet. She is safe, healthy, and happy now! Her rescuer says, “She is an adorable dog. She gets very excited whenever she sees me.”
Trial start date 6.27.22, Surgery date 8.1.22
Chloe’s ovarian follicles under a microscope. Her ovaries were removed during routine spay and neuter surgery, then preserved for analysis.
Chloe
Chloe was found by a 600 team member in an abandoned house, anxious and sad. She didn’t want to move at all. A neighbor told our team that Chloe’s family had moved abroad and left Chloe behind. It took a lot of time and work to get Chloe to trust humans again, but she is now safe and adored. She loves being around other dogs.
Crystal
When our 600 team member received a phone call about Crystal, residents in the area reported that she had three pups and one had recently died. The residents had tried to offer Crystal food, but she refused. When rescuers arrived, at first Crystal was fiercely protective of her remaining pups. But after a while, Crystal became comfortable with her rescuers, and she was moved to safety with her pups.
Trial start date 9.9.22, Surgery date 10.11.22
A microscopic image of Crystal’s ovarian follicles. One of the compounds we are examining to produce infertility is VCD: Vinylcyclohexene dioxide, CAS. No. 106-87-6, C8H12O2. As a multiple-dose formula, it has been studied for years, and it is already approved for use in the U.S. by the EPA to produce infertility in rodents.
Trial start date 9.9.22, Surgery date 10.11.22
Blair’s ovarian follicles will be analyzed to determine how many are rendered non-viable by certain compounds that cause infertility. Once enough viable follicles become non-viable, permanent infertility is the result. In adult human females, this is a safe and natural condition that occurs at menopause.
Blair
When Blair was rescued by a 600 team member, she was starving and surviving by eating garbage. She was depressed and thirsty and away from the other stray dogs. As soon as her rescuer offered her water and a treat, she perked up and wagged her tail. She already knew how to shake hands! After she was rescued, she became a much happier dog.
Sophie
When Sophie was found by a 600 team member, she had dug herself a hole and was hiding in it. She was miserable and terrified and had a bad case of worms. She was immediately brought to the veterinarian and treated. She is much happier now!
Trial start date 6.27.22, Surgery date 8.2.22
Sophie’s ovarian follicles under a microscope. In our current study, 30 days after each rescued Pilot Pup is given the One-Dose Spay and Neuter Cookie, the dog undergoes routine spay or neuter surgery. The reproductive tissues that are removed as part of the surgery – ovaries in females, testes in males – are preserved rather than discarded. This allows scientists to analyze the effectiveness of the Cookie.
Trial start date 6.7.22, Surgery date 7.6.22
Blaze's ovarian follicles under a microscope.
For the safety of the Pilot Pup, we only increase key ingredients by very small, controlled amounts, one tiny step at a time.
Trial start date 6.7.22, Surgery date 7.6.22
Ovarian follicles of Pilot Pup Lucky.
The more follicles that are impaired the better, and the closer the dog is to being infertile.
Blaze
When Blaze was rescued by a 600 team member, she was terrified of just about everything. Luckily, her rescuer was able to win her over with some treats! Now, Blaze enjoys all the treats she wants in her adopted home.
Lucky
Our 600 team members received a call that there was a dog barking in an abandoned area nearby. Lucky, a very active dog, was constantly barking, so residents were afraid to help her. Thankfully, a 600 team member arrived and brought her to our veterinarian. She is safe in her adopted home now!
Trial start date 4.17.22, Surgery date 5.17.22
Jasper’s ovary under a microscope.
Trial start date 4.17.22, Surgery date 5.17.22
Boomer’s ovary under analysis. Our previous studies produced our highest follicle counts to to date. The follicle count is basically the percentage of impaired follicles. Our goal is to safely increase the follicle count through further studies, until the number is high enough to cause permanent infertility.
Jasper
Jasper was rescued by a 600 team member from underneath a car. She was extremely lethargic…just skin and bones. She was taken to our veterinarian and is doing great now!
Boomer
Boomer’s rescuer, a 600 team member, describes her as “a very friendly and happy dog. She greets everyone with a big tail wag and a smile!” Now Boomer gets to spread her joy in her forever home!
Trial start date 4.28.22, Surgery date 5.28.22
Maple's ovarian follicles will be reviewed by multiple veterinary pathologists to determine the effectiveness of the Cookie she received.
Maple
Maple was rescued from a neighborhood a few miles away from the nearest shelter. Maple’s rescuer, a 600 team member, reported: “We received a call about a group of aggressive dogs causing trouble. When we got to the area, we were met with a group of terrified dogs. They weren’t aggressive, they were just in need of love.”
Trial start date 5.1.22, Surgery date 6.1.22
Pilot Pup Minnie's ovaries, removed during routine spay surgery. Under higher magnification, her ovarian follicles will be examined to determine the effectiveness of the Cookie she received.
Minnie
Minnie was found on the sidewalk of a busy road. “She was so skinny and was very depressed. She did not even respond to anything going on around her,” her rescuer said. But now, as a Pilot Pup, she has been adopted into a loving home!
Trial start date 5.2.22, Surgery date 6.2.22
Gracie’s ovary under the microscope, removed for analysis during routine spay and neuter surgery!
